Quanta Pharma Melatonin 10mg x 100 tablets

£32.00

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Quanta Pharma Melatonin 10mg x 100 Tablets

Quanta Pharma Melatonin 10mg x 100 tablets offers a high–concentration formulation of synthetic melatonin (N-acetyl-5-methoxytryptamine), a hormone critical for regulating circadian rhythms and sleep-wake cycles. Designed for rigorous scientific investigation, this product is essential for research into sleep disorders, jet lag models, neuroprotection, and antioxidant mechanisms. Unlike lower-dose supplements, the 10mg strength allows researchers to study the effects of supraphysiological doses on oxidative stress, immune modulation, and severe circadian disruption. Each bottle contains 100 tablets, providing a substantial supply for extended longitudinal studies on sleep architecture and hormonal regulation in animal models. Quanta Pharma ensures strict adherence to purity standards, guaranteeing a chemically stable and accurately dosed substance for reliable data collection.

Key Features

High-Dose Formulation: 10mg per tablet enables research into high-threshold physiological effects and antioxidant capacity
Extended Research Supply: 100-tablet configuration supports long-term protocols on chronic sleep deprivation or aging
Circadian Rhythm Modulation: Essential tool for studying the synchronization of biological clocks and sleep-wake cycles
Potent Antioxidant: Investigated for direct free radical scavenging and neuroprotective properties
Verified Purity: Manufactured with ≥99.8% chemical purity, verified by independent third-party HPLC testing
Stable Compound: Synthetic formulation ensures consistent potency and stability under various storage conditions
Quality Assurance: Produced in ISO-certified facilities under strict laboratory guidelines

Mechanism of Action

Melatonin functions primarily by binding to MT1 and MT2 melatonin receptors located in the suprachiasmatic nucleus (SCN) of the hypothalamus. Activation of MT1 receptors inhibits neuronal firing, promoting sleep onset, while MT2 receptor activation phase-shifts the circadian clock, regulating the timing of sleep. Beyond receptor-mediated effects, melatonin is a powerful direct antioxidant. It neutralizes hydroxyl radicals, singlet oxygen, and other reactive oxygen species, protecting cellular DNA, lipids, and proteins from oxidative damage. It also stimulates the activity of antioxidant enzymes like glutathione peroxidase and superoxide dismutase. This dual mechanism makes it a unique subject for research into sleep, aging, and neurodegenerative diseases.

Research Benefits

Sleep Induction: Significantly reduces sleep latency and improves sleep quality in insomnia models
Circadian Re-entrainment: Accelerates recovery from jet lag and shift-work disorder simulations
Neuroprotection: Protects neurons from oxidative stress, excitotoxicity, and apoptosis in neurodegenerative models
Antioxidant Activity: Scavenges free radicals and reduces systemic oxidative stress markers
Immune Modulation: Investigated for effects on immune response, inflammation, and cancer therapy adjuncts
Anti-Aging Studies: Used in research concerning longevity, mitochondrial function, and age-related decline

When to Use

This compound is suitable for research into insomnia, circadian rhythm sleep-wake disorders, jet lag, neurodegenerative diseases (Alzheimer’s, Parkinson’s), and oxidative stress-related conditions. Utilize Quanta Pharma Melatonin when studying high-dose antioxidant effects or severe circadian disruption. Ideal for models requiring potent sleep induction or neuroprotection. Appropriate for investigations into aging, cancer biology, and immune system modulation. Not suitable for treating mild sleep issues where lower doses are standard clinical practice.

Dosage Guidelines for Research

Standard Research Dosage: 10-20mg per day, administered shortly before the intended sleep period or light-dark cycle shift
High-Dose Protocols: Some neuroprotection or cancer studies may utilize higher doses under strict veterinary supervision
Cycle Duration: Varies widely from acute single-dose studies to chronic administration over several months
Administration: Oral ingestion; precise timing relative to light exposure is critical for circadian studies
Monitoring: Regular assessment of sleep patterns, hormonal levels, and behavioral changes required
Safety: Generally well-tolerated, but high doses may cause drowsiness, dizziness, or hormonal disruptions

Product Specifications

Compound: Melatonin (N-acetyl-5-methoxytryptamine)
Manufacturer: Quanta Pharma
Strength: 10mg per tablet
Quantity: 100 tablets per bottle
Chemical Class: Indoleamine hormone / Antioxidant
Purity: ≥99.8% (HPLC certified)
Form: Oral tablet
Storage: Store below 25°C in a dry, dark environment; protect from light
Shelf Life: 3 years from manufacture date
Usage: Laboratory research and animal studies only

Conclusion

Quanta Pharma Melatonin 10mg x 100 tablets is a vital resource for researchers investigating the complex interactions between circadian biology, oxidative stress, and neuroprotection. Its high-dose formulation allows for the exploration of therapeutic potentials beyond simple sleep aid, including significant antioxidant and anti-cancer properties. The 100-tablet supply ensures continuity in long-term studies, while the precise 10mg dosing enables investigation into high-threshold effects. With Quanta Pharma’s commitment to purity, this product supports high-integrity research into sleep disorders, neurodegenerative diseases, and aging. Strict adherence to ethical guidelines and monitoring protocols is essential when utilizing high doses of hormonal agents.