Quanta Pharma Telmisartan 40mg x 60 tablets

£36.00

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Quanta Pharma Telmisartan 40mg x 60 Tablets

Quanta Pharma Telmisartan 40mg x 60 tablets offers a high-purity formulation of telmisartan, a potent and selective angiotensin II receptor blocker (ARB) with unique peroxisome proliferator-activated receptor gamma (PPAR-γ) modulating activity. Designed for rigorous scientific investigation, this compound is essential for research into hypertension mechanisms, cardiovascular protection, metabolic syndrome, and renal dysfunction. Unlike other ARBs, telmisartan exhibits partial PPAR-γ agonist effects, making it a critical tool for studying the intersection of cardiovascular health and metabolic regulation. Each bottle contains 60 tablets of 40mg, providing a substantial supply for extended studies on blood pressure control, organ protection, and insulin sensitivity in animal models. Quanta Pharma ensures strict adherence to purity standards, guaranteeing researchers receive a chemically stable and accurately dosed substance for reliable data collection.

Key Features

Dual Mechanism Action: Unique combination of ARB activity and partial PAR-γ modulation for metabolic research
Long Half-Life: 24–hour duration of action allows for once-daily dosing in chronic study models
High Potency: 40mg tablets provide effective dosing for severe hypertension or organ damage models
Extended Research Supply: 60-tablet configuration supports long-term protocols on cardiovascular health
Verified Purity: Manufactured with ≥99.8% chemical purity, verified by independent third-party HPLC testing
Organ Protection: Extensively studied for nephroprotective and cardioprotective properties
Quality Assurance: Produced in ISO-certified facilities under strict laboratory guidelines

Mechanism of Action

Telmisartan functions by selectively blocking the binding of angiotensin II to the AT1 receptor. Angiotensin II is a potent vasoconstrictor that also promotes aldosterone secretion, sodium retention, and vascular remodeling. By inhibiting this pathway, telmisartan induces vasodilation, reduces blood pressure, and decreases cardiac load. Uniquely, telmisartan also acts as a partial agonist of PPAR-γ, a nuclear receptor involved in glucose and lipid metabolism. This dual action improves insulin sensitivity, reduces inflammation, and prevents vascular damage beyond simple blood pressure control. The compound’s long half-life ensures sustained receptor blockade, making it ideal for studying continuous therapeutic effects.

Research Benefits

Hypertension Control: Effectively lowers blood pressure in various animal models of hypertension
Metabolic Improvement: Enhances insulin sensitivity and glucose metabolism via PPAR-γ modulation
Cardiac Protection: Prevents left ventricular hypertrophy and reduces myocardial fibrosis
Renal Preservation: Protects against diabetic nephropathy and proteinuria in kidney disease models
Anti-Inflammatory Effects: Reduces vascular inflammation and oxidative stress markers
Stroke Prevention: Investigated for neuroprotective effects and stroke risk reduction in hypertensive models

When to Use

This compound is suitable for research into hypertension, heart failure, diabetic nephropathy, metabolic syndrome, and stroke prevention. Utilize Quanta Pharma Telmisartan when studying the benefits of dual ARB and PPAR-γ modulation. Ideal for models requiring long-term blood pressure control with metabolic benefits. Appropriate for investigations into organ protection mechanisms and the prevention of cardiovascular remodeling. Not suitable for acute hypertensive emergencies requiring immediate intravenous intervention.

Dosage Guidelines for Research

Standard Research Dosage: 40-80mg per day, administered once daily due to long half-life
Cycle Duration: Typically used in long-term protocols ranging from 8 weeks to several months
Administration: Oral ingestion with or without food; consistent timing is recommended
Monitoring: Regular assessment of blood pressure, renal function, electrolytes (especially potassium), and glucose levels
Discontinuation: Gradual tapering may be required depending on the specific research protocol and model stability
Safety Protocols: Strict veterinary supervision required to manage risks of hypotension and hyperkalemia

Product Specifications

Compound: Telmisartan
Manufacturer: Quanta Pharma
Strength: 40mg per tablet
Quantity: 60 tablets per bottle
Chemical Class: Angiotensin II Receptor Blocker (ARB) with PPAR-γ modulating activity
Purity: ≥99.8% (HPLC certified)
Form: Oral tablet
Storage: Store below 25°C in a dry, dark environment
Shelf Life: 3 years from manufacture date
Usage: Laboratory research and animal studies only

Conclusion

Quanta Pharma Telmisartan 40mg x 60 tablets represents a sophisticated tool for researchers investigating the complex interplay between cardiovascular health and metabolic function. Its unique dual mechanism of action distinguishes it from other antihypertensive agents, offering valuable insights into organ protection and metabolic regulation. The long half-life and high potency make it suitable for chronic studies requiring stable, continuous intervention. With Quanta Pharma’s commitment to purity and accuracy, this product enables high-integrity research into hypertension, diabetes, and cardiovascular disease. Strict adherence to ethical guidelines and monitoring protocols is essential to manage the potent physiological effects of this compound.